General Cell Based Assays
Abcam Glutathione Peroxidase Activity Assay Kit (Fluorometric)
Glutathione Peroxidase Activity Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress EBI2 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0437E2ACP21M)
The PathHunter EBI2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. hydroxycholesterols) based activation of EBI2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged EBI2 and EA-tagged β-Arrestin-2. Activation of EBI2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mEDG1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0476E2MCP4L)
The PathHunter mEDG1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. S1P) based activation of mEDG1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mEDG1 and EA-tagged β-Arrestin-2. Activation of mEDG1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress ACVR1B/BMPR2 Dimerization Assay, 10pl Kit. (93-1072E3CP5L)
The PathHunter ACVR1B/BMPR2 Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. activin A) induced dimerization of ACVR1B/BMPR2 receptors. This product uses EFC technology. The cell line included overexpresses ACVR1B target protein fused to PK alongside BMPR2 target protein fused to EA. Upon ligand-induced dimerization of ACVR1B/BMPR2, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress OPRD1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0400E2CP2M)
The PathHunter OPRD1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. DADLE) based activation of OPRD1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRD1 and EA-tagged β-Arrestin-2. Activation of OPRD1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR92 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0372E2CP6L)
The PathHunter GPR92 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. LPA) based activation of GPR92 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR92 and EA-tagged β-Arrestin-2. Activation of GPR92 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery RPLEX HUM Thrombomodulin ASY
The R-Plex Human Thrombomodulin Assay from Meso Scale Discovery is a multiplex immunoassay that measures thrombomodulin levels in human serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to a 7-log dynamic range and low sample volume requirements The assay can monitor thrombomodulin levels as a biomarker of endothelial cell activation and damage It is available as a singleplex or as a multiplex with other cardiovascular disease biomarkers The R-Plex assay delivers rapid results in just 3 5 hours
Eurofins Discoverx PathHunter eXpress TACR1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0344E2CP0M)
The PathHunter TACR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. substance P) based activation of TACR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR1 and EA-tagged β-Arrestin-2. Activation of TACR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Isocitrate Dehydrogenase Assay Kit (Colorimetric)
Isocitrate Dehydrogenase Assay Kit (Colorimetric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human BMP-9 (ACVRL1/ACVR2) Dimerization Cell-Based Assay Kit (U2OS)
The PathHunter Human BMP-9 (ACVRL1/ACVR2) Stable Cell Line Dimerization Assay (U2OS) measures ligand-induced dimerization of ACVRL1/ACVR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Indigo Biosciences Human Oxytocin Receptor (OXTR) All-inclusive Cell-Based Luciferase Reporter Assay Kit, 96-well assay plate format
Eliminate weeks of cell culture while achieving superior sensitivity with reproducible results from this all-inclusive cell-based luciferase reporter assay. INDIGO’s Human Oxytocin Receptor (OXTR) reporter assay allows you to quickly screen test samples to quantify functional activity, either agonist or antagonist, they may exert against OXTR. Kit includes cryopreserved reporter cells engineered to provide constitutive expression of the receptor, optimized media for use during cell thawing and in diluting test samples, reference agonist, Luciferase Detection Reagent, cell culture-ready assay plate, and detailed assay protocol. INDIGO’s unique Cryomite™ process provides exceptional cell viability post-thaw and INDIGO’s strict QA process means consistent results lot to lot (product quality data available upon request). This kit allows researchers to achieve superior sensitivity, clear, reproducible results, and eliminate weeks of cell culture work.
Meso Scale Discovery U-PLEX Human VEGF-a ASY
The Meso Scale Discovery U-PLEX Human VEGF-A Assay Kit is a multiplex immunoassay that measures VEGF-A levels in human serum plasma and cell culture supernatants It uses electrochemiluminescence detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay has high specificity and low cross-reactivity It includes a plate coated with capture antibodies detection antibodies labeled with electrochemiluminescent labels calibrator and buffer The kit allows quantification of VEGF-A levels with a lower limit of detection of 0 06 pg/mL
Eurofins Discoverx PathHunter eXpress cyno GPR120 CHO-K1 β-Arrestin GPCR Assay, 10pl Kit. (93-1029E2CP0L)
The PathHunter cyno GPR120 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. free fatty acids) based activation of cyno GPR120 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged cyno GPR120 and EA-tagged β-Arrestin-2. Activation of cyno GPR120 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress ErbB2-ErbB3 Functional Assay, 10pl Kit. (93-0535E3CP16L)
The PathHunter eXpress ErbB2-ErbB3 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated ErbB2 and ErbB3 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged ErbB2 and an EA-tagged SH2 domain protein. It also overexpresses an untagged coreceptor, ErbB3 Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human TACR1 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human TACR1 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure TACR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.